This research is targeting patients with sonographically indeterminate adnexal mass that are being referred for clinical MR imaging. Investigators from the UW will be contributing coded MR images and associated health information (US results, laboratory/pathology results) to the EURAD trial. In addition, outcomes data on each patient will be sent at month 24 of the research.
An adnexal mass is the most common indication for gynaecological surgery. Pre operative characterization is crucial and a scoring system would be useful to standardize the imaging report and thus, improve patients management. Recently, the coordinating center developed the first MR scoring system named ANDEXMR SCORING system in a retrospective study which is accurate and reproducible. The objectives of this trial are to perform an external prospective validation of this scoring system to evaluate its potential impact on therapeutic strategy and to test its reproducibility. This is a prospective large multicenter study. All patients with a sonographically indeterminate adnexal mass referred for MR imaging will be included from each participating center. One senior and one junior radiologists independently analyze the different MR criteria to characterize adnexal masses. The reader will then classify the mass using ADNEXMR SCORING system.
Study Type
OBSERVATIONAL
Enrollment
1,340
Scoring system used to standardize the imaging report for sonographically indeterminate adnexal masses.
University of Wisconsin
Madison, Wisconsin, United States
Reproducibility of the ADNEX MR scoring system between centers
Evaluate if ADNEXMR SCORING system is relevant for reporting pelvic magnetic resonance imaging (MRI) examinations performed for characterization of sonographically indeterminate adnexal masses in an external prospective multicenter study
Time frame: 24 months
Differences in rate of surgery in women with adnexal lesions in those where the ADNEX MR score is used compared to when it is not used.
The potential impact of applying the score to the therapeutic strategy, in particular to measure the possible reduction in unnecessary surgery in benign cases.
Time frame: 24 months
Reproducibility of the score
If ADNEXMR SCORING system improves reproducibility of MR report for characterization of adnexal masses
Time frame: 24 months
Comparison between a blinded and an unblinded radiologist regarding sonographic data
If ADNEXMR SCORING system is as accurate if the radiologist is blinded from any clinical and ultrasonographic data
Time frame: 24 months
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