CRRT for Glutamate Elimination After Cardiac Arrest

C. Storm42 enrolled

Overview

Glutamate is known to be a mediator for apoptosis after brain hypoxia e.g. due to cardiac arrest. This pilot trial evaluates the possibility of elimination of Glutamate by CRRT after cardiac arrest.

Study Type

INTERVENTIONAL

Allocation

RANDOMIZED

Purpose

TREATMENT

Masking

NONE

Enrollment

Conditions

Reperfusion Syndrome

Interventions

Continuous renal replacement therapyPROCEDURE

Eligibility

Sex: ALLMin age: 18 Years

Medical Language ↔ Plain English

Inclusion Criteria: * post cardiac arrest Exclusion Criteria: * hemodynamic instable * in-hospital cardiac arrest

Locations (1)

Charité-Universitätsmedizin Berlin

Berlin, Germany

Outcomes

Primary Outcomes

Glutamate blood concentration in intervention arm over the time

Reduction of blood Glutamate concentration by renal replacement therapy

Time frame: 72 hours

Secondary Outcomes

number of participants with abnormal outcome parameters

Time frame: up to 14 days

Data from ClinicalTrials.gov

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