Development and Clinical Validation of Ketogen-based Therapeutic Diet for Pancreaticobiliary Cancer Patients

Yonsei University30 enrolled

Overview

Decreased bowel function and loss of appetite in patients who underwent pancreaticobiliary surgery contribute impaired nutritional status in postoperative period. It can also affect perioperative and oncologic outcomes negatively. Therefore it is important to improve nutritional status in postoperative period by supply tailor-made optimal diets. The investigators have developed customized postoperative diets for pancreaticobiliary cancer patients. The investigators expect that customized diets for pancreaticobiliary patients will increase the food intake rate and contribute a improvement of perioperative outcomes and even oncologic outcomes.

Study Type

INTERVENTIONAL

Allocation

NON_RANDOMIZED

Purpose

SUPPORTIVE_CARE

Masking

NONE

Enrollment

Conditions

Ketogen-based Therapeutic Diet Pancreaticobiliary Cancer

Interventions

Eligibility

Sex: ALLMin age: 19 YearsMax age: 80 Years

Medical Language ↔ Plain English

Inclusion Criteria: * Adult (age more than 19) * Pancreaticobiliary cancer patient who is scheduled pancreaticoduodenectomy or distal pancreatectomy * Pancreatic cancer / Duodenal cancer / Distal bile duct cancer / Ampulla of Vater cancer Exclusion Criteria: * Patient who denied clinical trial * Diabetes Mellitus(DM) patient with DM complication * Hyperlipidemia patient with vascular co-morbidity * Impaired renal function or renal failure (GFP\<90%)

Outcomes

Primary Outcomes

Food Intake Rate(%) for postoperative diet

Diet Intake Rate(%) will be examined by dietary satisfaction questionnaires.

Time frame: 3 days after the diet