Patients who have undergone the Fontan procedure (a congenital heart surgery) may develop complications many years after their operation. Studies have shown that some of these patients develop an ongoing inflammatory state, which may be the cause of these late complications. Aspirin is a common over the counter anti-inflammatory medication used for many other chronic diseases. This study may help determine if aspirin therapy can limit the inflammation seen in Fontan patients and prevent these late complications.
Study Type
INTERVENTIONAL
Allocation
NA
Purpose
TREATMENT
Masking
NONE
Enrollment
9
University of Michigan
Ann Arbor, Michigan, United States
Change in Total Cholesterol
Change will be measured from baseline to retest after 8 weeks of treatment
Time frame: 8 weeks
Change in HDL (High-Density Lipoprotein)-Cholesterol
Change will be measured from baseline to retest after 8 weeks of treatment
Time frame: 8 weeks
High Sensitivity CRP(C-Reactive Protein)
Change will be measured from baseline to retest after 8 weeks of treatment
Time frame: 8 weeks
Quality of Life
The Medical Outcomes Short-Form 36-Item Health Survey (SF-36) is a standardized health survey consisting of 36 questions that measure 8 dimensions of general health-related quality of life: physical functioning, role limitation due to physical health problems, bodily pain, general health perceptions, vitality, social functioning, role limitations due to emotional problems, and general mental health. The score is represented as an average of the individual question scores, and ranges from 0 (not functioning) to 100 (highest functioning). Higher scores indicate a better health status.
Time frame: 8 weeks
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