Effect of Sedatives on Regional Cerebral Oxygen Saturation

Gachon University Gil Medical Center

Overview

Compare the changes of regional cerebral oxygen saturation during midazolam or dexmedetomidine sedation for spinal anesthesia in the elderly patients who undergoing femur surgery.

Compare the changes of regional cerebral oxygen saturation during midazolam or dexmedetomidine administration (target bispectrl index 75-80) for spinal anesthesia in the elderly patients over 65 years who undergoing femur surgery.

Study Type

INTERVENTIONAL

Allocation

RANDOMIZED

Purpose

OTHER

Masking

DOUBLE

Conditions

Cerebral Ischemia-Hypoxia

Interventions

MidazolamDRUG

administration of midazolam during spinal anesthesia for target bispectral index 75-80

DexmedetomidineDRUG

administration of dexmedetomidine during spinal anesthesia for target bispectral index 75-80

Eligibility

Sex: ALLMin age: 65 Years

Medical Language ↔ Plain English

Inclusion Criteria: * patinets who undergoing femur surgery under spinal anesthesia Exclusion Criteria: * previous cerebrovascular disease, uncontrolled cardiovascular disorder, uncontrolled pulmonary disease

Locations (1)

Gachon University Gil Hospital

Incheon, South Korea

Outcomes

Primary Outcomes

regional cerebral oxygen saturation

Time frame: 1 day

Data from ClinicalTrials.gov

This platform is for informational purposes only and does not constitute medical advice. Always consult a qualified healthcare professional.