NSAID Treatment of Patients With Osteoarthritis

Aalborg University162 enrolled

Overview

The study investigates associations between pre treatment pain intensity and central pain mechanisms on the effect of 8-week treatment of NSAIDs in patients with knee osteoarthritis.

Study Type

INTERVENTIONAL

Allocation

Purpose

DIAGNOSTIC

Masking

NONE

Enrollment

162

Conditions

Osteoarthritis,Knee

Interventions

NSAIDDRUG

NSAIDs are among the most common pain treatments for patients with osteoarthritis.

Eligibility

Sex: ALLMin age: 18 YearsMax age: 80 Years

Medical Language ↔ Plain English

Inclusion Criteria: * Diagnosed Knee Ostoarthritis Exclusion Criteria: * Current ulcer diagnosed by endoscope * Asthma or other allergic reaction to NSIADs * Kidney disease * Myocardial infarction within the last six months * Severe hyper tension (systolic ≥180mmHg, diastolic ≥110mmHg) * Severe thrombocytopenia (thrombocyst count \<50x10\^9/l) * Insufficience lever or kidney function

Locations (1)

Center for Sensory Motor Interaction, Aalborg University

Aalborg East, Denmark

Outcomes

Primary Outcomes

Pain intensity measured on a 10cm visual analog scale

Patients will be asked to rate the pain intensity 8 weeks after treatment on a 10cm visual analog scale (0 indicating no pain, 10 indicating worst imaginable pain

Time frame: 8 weeks after treatment

Data from ClinicalTrials.gov

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