A RCT on Supraglottic Airway Versus Endotracheal Intubation in OHCA

National Taiwan University Hospital852 enrolled

Overview

In this 3-year successive research plan, investigators will conduct a prehospital randomized controlled trial to address the following question: In adult patients with non-traumatic cause of out-of-hospital cardiac arrest resuscitated by emergency medical technician (paramedic level) in the prehospital setting, will receiving endotracheal tube intubation cause a better chance of sustained recovery of spontaneous circulation and other survival outcomes like neurologically favorable status, comparing to those who receiving supraglottic airway device.

Study Type

INTERVENTIONAL

Allocation

RANDOMIZED

Purpose

TREATMENT

Masking

DOUBLE

Enrollment

852

Conditions

Prehospital Airway Management in Patients With Cardiac Arrest

Interventions

supraglottic airway (SGA) V.S. endotracheal intubation (ETI)DEVICE

already being described above

Eligibility

Sex: ALLMin age: 20 Years

Medical Language ↔ Plain English

Inclusion Criteria: * out-of-hospital cardiac arrest; OHCA * age ≥ 20 years old * non-traumatic cause Exclusion Criteria: * signs of obvious death, eg. decapitation or rigor mortis * theoretically not suitable for ETI, eg. facial deformity or third-trimester pregnancy * theoretically not suitable for SGA, eg. foreign-body airway obstruction * with "do not attempt resuscitation" order * the occurrence of OHCA during ambulance transport * ROSC in the field with clear consciousness and spontaneous adequate ventilation * advanced airway being established before the arrival of paramedics

Outcomes

Primary Outcomes

survival to admission

Measurement of outcome by standard Utstein OHCA registry system in Taipei City

Time frame: One month after event

Secondary Outcomes

any ROSC

Measurement of outcome by standard Utstein OHCA registry system in Taipei City

Time frame: One month after event

survival to discharge

Measurement of outcome by standard Utstein OHCA registry system in Taipei City

Time frame: One month after event

favorable neurologic outcome

Favorable neurologic outcome was defined by CPC (cerebral performance category) 1 and 2. Measurement of outcome by standard Utstein OHCA registry system in Taipei City

Time frame: One month after event

Central Contacts

Wen-Chu Chiang, MD, PhD.

CONTACT

+886-2-23123456 drchiang.tw@gmail.com

Data from ClinicalTrials.gov

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