Clinical Study of Targeted Cryoablation Therapy in the Treatment of Hepatic Carcinoma

Shanghai University of Traditional Chinese Medicine30 enrolled

Overview

The purpose of this study is to evaluate the safety and efficacy of targeted cryoablation therapy for hepatic carcinoma.

A cryoprobe is inserted percutaneously under CT guidance into the targeted lesion. Patients undergo ablation using a freeze-thaw-freeze cycle lasting approximately 10-6-10minutes.

Study Type

INTERVENTIONAL

Allocation

Purpose

TREATMENT

Masking

NONE

Enrollment

Conditions

Liver Neoplasms

Interventions

Targeted Cryoablation TherapyPROCEDURE

A cryoprobe is inserted percutaneously under CT guidance into the targeted lesion. Patients undergo ablation using a freeze-thaw-freeze cycle lasting approximately 6-10-6 or 8-10-8 minutes, respectively.

Eligibility

Sex: ALLMin age: 18 YearsMax age: 75 Years

Medical Language ↔ Plain English

Inclusion Criteria: * Diagnosis of liver cancer based on histology or the current accepted radiological measures. * Single Tumor size ≤5.0 cm in greatest diameter, or multiple tumor number≤3 and each tumor size≤ 3cm. * Life expectancy: Greater than 3 months. * Patients' liver function is Child-pugh A or B. * Ability to understand the study protocol and a willingness to sign a written informed consent document. * Unable to receive operative surgery. Exclusion Criteria: * Patients with other primary tumor except liver cancer. * History of coagulation disorders or anemia.

Locations (1)

Shanghai Longhua Hospital

Shanghai, Shanghai Municipality, China

Outcomes

Primary Outcomes

Rate of complete tumor ablation

Time frame: Up to 4 weeks post surgery

Secondary Outcomes

Adverse Events

Time frame: Up to 4 weeks post surgery

Data from ClinicalTrials.gov

This platform is for informational purposes only and does not constitute medical advice. Always consult a qualified healthcare professional.