Detection of Airway Obstruction by Manometry in Different Sleep Stages and Comparing it to DISE

Technical University of Munich30 enrolled

Overview

Patients with OSA receive manometry measurements with Apneagraph (AG) during one night of sleep. All patients are simultaneously evaluated with polysomnography. Patients who are not eligible for CPAP therapy are additionally studied with drug-induced sleep endoscopy (DISE). The frequency and obstructions patterns in different sleep stages are assessed. In addition obstruction patterns detected with AG are compared with DISE examination in the selected cases.

Study Type

OBSERVATIONAL

Enrollment

Conditions

Sleep Apnea Syndromes

Interventions

Manometry and possibly DISEDEVICE

A Manometry is performed on all patients. After it in some Patient DISE is followed

Eligibility

Sex: ALLMin age: 18 Years

Medical Language ↔ Plain English

Inclusion Criteria: * Apnea-Hypopnea-Index (AHI) ≥ 5. Exclusion Criteria: * age \<18 years; * body mass index (BMI) of \>35 kg/m2; active infection; * previous oral, head, or neck surgery in the last 3 months; pregnancy; chronic use of alcohol (\> 60g ethanol per day or \> 150g ethanol per week) or sedatives; illicit drug use; * chronic obstructive pulmonary disease.

Locations (1)

Klinik für Hals- Nasen- Ohrenheilkunde

München, Bavaria, Germany

RECRUITING

Outcomes

Primary Outcomes

Detection of obstruction depending of sleep stage

Time frame: 8

Secondary Outcomes

Comparing the manometry findings to DISE

Time frame: 1 Hour

Central Contacts

Clemens Heiser, MD

CONTACT

+49 8941409583 hno@heiser-online.com

Günther M Edenharter, MD

CONTACT

+49 89 41405051 g.edenharter@tum.de

Data from ClinicalTrials.gov

This platform is for informational purposes only and does not constitute medical advice. Always consult a qualified healthcare professional.