Efficacy and Safety of Eyetronix Flicker Glasses to the Treatment of Anisometropic Amblyopia

Inclusion Criteria: 1. aged from 4 to 13 years old 2. the best corrected visual acuity in the amblyopic eye is no more than 0.1logMAR, with two lines or more of difference between the two eyes 3. anisometropia is defined as an inter-ocular spherical refractive error difference of 1.00 D or more or a cylindrical difference of 1.50 D or more. 4. no amblyopia treatment one month prior to the study except refractive correction. 5. myopia is less than -6.00D or hyperopia is less than +9.00D, strabismus was less than 20 prism diopters 6. willing to participate in this study and be able to follow up on time Exclusion Criteria: 1. ocular disease and other disease that have an influence on the visual acuity 2. history of ocular surgery that have an influence on the visual acuity 3. the patient is receiving other amblyopia treatment except refractive correction 4. a family or personal history of seizures 5. the patient is using some medicine that may have an influence on visual acuity