Thromboelastometry in Assessment of Sepsis Coagulopathy

University Hospital, Motol76 enrolled

Overview

The purpose of this study is to analyze occurence of bleeding complications during invasive procedures in septic patients with normal tromboelastometry results despite prolonged standard coagulation tests results

Study Type

OBSERVATIONAL

Enrollment

Conditions

Thrombelastography Sepsis

Eligibility

Sex: ALLMin age: 24 YearsMax age: 89 Years

Medical Language ↔ Plain English

Inclusion Criteria: * sepsis/septic shock * prolonged PT-INR (international normalized ratio) ≥ 1.3 * normal ROTEM-EXTEM results. Exclusion Criteria: * patients on antiplatelet drugs or anticoagulant therapy (heparin, vitamin K antagonists…) * patients with cirrhosis

Outcomes

Primary Outcomes

incidence of bleeding complications

In our group of 76 septic patients who had normal values of EXTEM despite prolonged INR/PR invasive procedures were performed without severe bleeding.

Time frame: 2013 - 2016

Data from ClinicalTrials.gov

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