ARDS is a critical respiratory disease caused by endogenous and exogenous factors. The mortality of ARDS varies from 30 to 70%. In 2012, a new international diagnostic criterion has been put forward. Yet, its feasibility, reliability and validity need to be tested. Meanwhile, the correlation of different severity and prognosis remains unclear. As so far, the epidemiological information about ARDS in China is lacking. Investigators plan to conduct a multi-center observational study（real-life study） to investigate the risk factors, morbidity, management and prognosis of ARDS in China, in order to facilitate standardization of diagnosis and management of ARDS and provide basic data and idea for further clinical intervention studies.
Study Type
OBSERVATIONAL
Enrollment
400
China - Japan Friendship Hospital
Beijing, Beijing Municipality, China
Mortality
the 28days mortality after the diagnosis of ARDS
Time frame: 28days
Length of ICU stay
The days between admission to intensive care unit(ICU) and discharge from ICU.
Time frame: 90 days
Ventilation free days
The days between successful weaning from mechanical ventilation and day 28 after study enrollment.
Time frame: 28 days
Incidence of ARDS
The total number of acute respiratory distress syndrome(ARDS)patients in 2 years.
Time frame: 2 years
Severity of patients
Number of patients in each grade of severities according to Berlin definition: the number of mild, moderate and severe acute respiratory distress syndrome(ARDS) patients will be recorded.
Time frame: 2 years
Adverse events related to treatment
Number of patients with adverse events, include biotrauma, worsen of hemodynamics, hospital-acquired infection, patient-ventilator asynchrony, gastric distention, aspiration etc.
Time frame: 90 days
Number of patients using adjuvant drugs
Adjuvant drugs refer to corticosteroid, sedative, analgesic and non depolarizing muscle relaxant.
Time frame: 28 days
Number of patients with high risk factors
High risk factors for acute respiratory distress syndrome(ARDS), including endogenous factors as pneumonia, aspiration, lung contusion and drowning; the exogenous factors as extrapulmonary trauma, extra pulmonary sepsis , hypovolemic shock, pancreatitis, severe burning, drug overdose, blood transfusion，eclampsia etc.
Time frame: 1 week
Number of patients with conventional respiratory support techniques
Conventional respiratory support techniques include noninvasive positive pressure ventilation(NPPV), invasive positive pressure ventilation(include volume-controlled ventilation and pressure-controlled ventilation) .
Time frame: 28 days
Number of patients with unconventional respiratory support techniques
Unconventional respiratory support techniques include recruitment maneuver(RM), prone position ventilation(PPV), high-frequency oscillatory ventilation(HFOV) ,extracorporeal membrane oxygenation(ECMO) and extracorporeal CO2 removal(ECCO2R)
Time frame: 28 days
Number of patients with impaired lung function
The number patients with impaired lung function 90 days and 1 year after diagnosis of acute respiratory distress syndrome(ARDS).
Time frame: 90 days, 1 year
Number of patients with abnormal lung CT
The number patients with abnormal lung CT 90 days and 1 year after diagnosis of acute respiratory distress syndrome(ARDS).
Time frame: 90 days, 1 year
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