1. To build an imaging biobank of 200 patients with lungcancer, including pathologic and molecular characteristics of the tumor (mutational status, circulating DeoxyriboNucleic Acid (DNA) from serum biobank…), staging of the cancer (according to the new 2016 Tumor Node Metastasis (TNM) status, the table that classify non-small cell lungcancer) and follow-up informations (Response to first-line treatment (Response Evaluation Criteria in Solid Tumors (RECIST)), disease-free survival, 1-3 years survival). 2. To propose a simple severity scoring system based on tumor features such as size, doubling time (if available), location, amount of enhancement and necrosis. Such approach has been proposed for glioma evaluation (Visually Accessible Rembrandt Images (VASARI)) but is not available for the lung. The objective is to do better than the Tumor Node Metastasis (TNM) staging. 3. To develop and evaluate an IntraVoxel Incoherent Motion (IVIM) protocol for lungcancer evaluation.
Study Type
INTERVENTIONAL
Allocation
NA
Purpose
OTHER
Masking
NONE
Enrollment
200
* Chest MRI during the MRI cerebral * 2 tubes of blood taken during the medical visit
BRILLET
Bobigny, France
RECRUITINGEvent-free survival of patients with lungcancer
Time frame: 3 years
Overall survival
Time frame: 3 months, 1 year, 2 years and 3 years
Number of patients by histologic subtypes
Time frame: 3 months, 1 year, 2 years and 3 years
Number of patients by mutational profile
Time frame: 3 months, 1 year, 2 years and 3 years
Number of patients with metastases
Time frame: 3 months, 1 year, 2 years and 3 years
Number of patients with brain metastases
Time frame: 3 months, 1 year, 2 years and 3 years
Number of metastases by patient
Time frame: 3 months, 1 year, 2 years and 3 years
Therapeutic responses assessed by scanner/MRI and/or Positron Emission Tomography (PET) based on consensus criteria (RECIST 1.1 and PET Response Criteria in Solid Tumors (PERCIST))
Time frame: 3 months, 1 year, 2 years and 3 years
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