Postspinal Hypotension and Cardiac Performance in the Elderly

Karolinska Institutet20 enrolled

Overview

Patients, scheduled for elective arthroplasty were monitored with Lithium Dilution Cardiac Output monitor (LiDCOplus™) before and 45 minutes after spinal anesthesia. Hypotension was defined as systolic blood pressure ≤ 100 mmHg or ≥ 30% decrease from baseline. Associations between hypotension and the hemodynamic changes after preanaesthetic fluid loading and spinal anesthesia were analysed by logistic regression analyses.

Study Type

OBSERVATIONAL

Enrollment

Conditions

ARTHROPLASTY, REPLACEMENT; ANESTHESIA

Interventions

Spinal anaesthesiaOTHER

Eligibility

Sex: ALLMin age: 65 Years

Medical Language ↔ Plain English

Inclusion Criteria: * hip or knee arthroplasty * spinal anaesthesia * age 65 years or more Exclusion Criteria: * weight \<40kg * concomitant lithium medication * written informed consent not obtained * research team unavailable

Outcomes

Primary Outcomes

Stroke volume in ml

the blood volume pumped by the heart at each stroke

Time frame: 0-45 minutes after spinal anaesthesia

Secondary Outcomes

Arterial blood pressure mmHg and change from baseline

mmHg measured by arterial catheter

Time frame: 0-45 minutes after spinal anaesthesia

Data from ClinicalTrials.gov

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