CBT for Adolescents With Excessive Worry

Karolinska Institutet12 enrolled

Overview

This case series aims to test the feasibility and acceptability of streamlined cognitive behavioral therapy (CBT) for adolescents with excessive worry. The treatment protocol focuses on reducing intolerance of uncertainty and the hypothesis is that this will help reduce worry.

This pilot study aims to test a new form of Cognitive Behavioral Therapy for adolescents with excessive worry. The investigators will include 12 participants with excessive worry and test the treatment which focuses on reducing intolerance of uncertainty (IU) in order to reduce worry. Participants will be randomized to either one, two or three weeks of weekly baseline measurements prior to starting treatment, and will thus work as their on controls in this case series design. Primary outcome measures will be collected at 12 weeks after treatment start. Participants will be followed up at three months after treatment.

Study Type

INTERVENTIONAL

Allocation

Purpose

TREATMENT

Masking

NONE

Enrollment

Conditions

Excessive Worry

Interventions

Cognitive behavioral therapyBEHAVIORAL

CBT focused on reducing intolerance of uncertainty

Eligibility

Sex: ALLMin age: 13 YearsMax age: 17 Years

Medical Language ↔ Plain English

Inclusion Criteria: * A score on PSWQ-C of at least 22 * Age between 13 and 17 years * Ability to read and write in Swedish * A parent or caregiver that is able to co-participate in the treatment * Participants on psychotropic medication must have been on a stable dose for the last 6 weeks prior to baseline assessment Exclusion Criteria: * Diagnosis of autism spectrum disorder, psychosis, bipolar disorder or severe eating disorder * Present risk of suicide * Ongoing substance dependence * Occurrence of domestic violence * Completed CBT for any anxiety disorder within the last 6 months (defined as at least 5 sessions of CBT including in vivo exposure sessions)

Locations (1)

Karolinska Institutet

Stockholm, Sweden

Outcomes

Primary Outcomes

Penn State Worry Questionnaire for Children (PSWQ-C)

Child and parent version

Time frame: At 12 weeks after treatment starts

Secondary Outcomes

Mini International Neuropsychiatric Interview for Children and Adolescents (MINI-KID)

Diagnostic interview

Time frame: Baseline, 12 weeks after start of treatment and three month after treatment has ended.

Clinical Global Impression - Severity (CGI-S)

Clinician rated severity of symptoms

Time frame: Baseline, 12 weeks after start of treatment and three month after treatment has ended.

Clinical Global Impression - Improvement (CGI-I)

Clinician rated improvement after treatment

Time frame: At 12 weeks after start of treatment and three month after treatment has ended.

Children's Global Assessment Scale (CGAS)

Clinician rated global functioning

Time frame: Baseline, 12 weeks after start of treatment and three month after treatment has ended.

Brief Intolerance of Uncertainty Scale (Brief IUS)

Self rated tolerance to treatment

Time frame: Baseline, weekly during treatment, 12 weeks after treatment starts, and three months after treatment has ended

Brief Cognitive Avoidance Questionnaire (Brief CAQ)

Self rated cognitive avoidance

Time frame: Baseline, weekly during treatment, 12 weeks after treatment starts, and three months after treatment has ended

Data from ClinicalTrials.gov

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