Italian Multi-center Registry of Self-apposing Coronary Stent in Patients With STEMI

Inclusion Criteria: * Patients 18 years of age and older presenting with symptoms consistent with a ST-Elevation Myocardial Infarction (STEMI) lasting ≤12 hrs in duration, with ≥2 mm of ST-segment elevation in ≥2 contiguous leads, treated with primary stent implantation (Xposition S planned per operator's assessment). Exclusion Criteria: * Cardiogenic shock * Multiple lesions requiring stenting in the target vessel. * Highly calcified lesions or excessive tortuosity at target lesion site. * Intrastent pathology. * Subject unable to take or comply with dual antiplatelet therapy as recommended per guidelines. * Female subjects of childbearing potential known to be pregnant. * Co-morbidities with life expectancy less than 1 year * Patient unable to provide written informed consent. * Known allergies to stent component.