Breast cancer related lymphedema (BRCL) is a common complication following breast cancer treatment. The incidence of BRCL ranges from 6-50%, depending on the surgical procedure in the axilla and the type of the radiation therapy. BRCL can causes cosmetic deformities, impaired physical mobility, mental discomfort, reduced quality of life and erysipelas. Therapy of BRCL is divided into conservative and operative methods. However, all the above method has some shortcomings. It is urgent to investigate new approaches to treat BRCL. In this study, fat grafting is to be used for the treatment of BRCL, and the efficacy and safety of this method will be also assessed.
Study Type
INTERVENTIONAL
Allocation
NA
Purpose
TREATMENT
Masking
NONE
Enrollment
30
Treatment of breast cancer related lymphedema by fat grafting
Plastic Surgery Hospital of Chinese Academy of Medical Sciences, Peking Union Medical College
Shijingshan, Beijing Municipality, China
RECRUITINGChange in arm volume
All the patients who received treatment are scanned by 3 dimensional camera, then the volume measurement of the affected and normal arm is managed by software
Time frame: Baseline, 3 months, 6months and 12 months
Change in tissue edema
The affected and normal arms of the patients who received treatment are assessed by multi-frequency bioelectrical impedance analysis
Time frame: Baseline, 3 months, 6months and 12 months
The function of the lymphatic vessel
The affected arms of the patients who received treatment was assessed by indocyanine green lymphography
Time frame: Baseline, 3 months, 6months and 12 months
Side effects of treatment
Any side effects of experimental treatment. The patients who received treatment are asked at each visit
Time frame: Baseline, 3 months, 6months and 12 months
Change in quality of life
The patients who received treatment are asked to fill in a questionnaire (EQ-5D- 5 L-questionnaire)
Time frame: Baseline and 12 months
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