Weaning Outcome From Invasive Mechanical Ventilation

Beijing Chao Yang Hospital300 enrolled

Overview

The main purpose of the present study was to explore the weaning failure rate from invasive mechanical ventilation and to identify risk factors of weaning failure.

Study Type

OBSERVATIONAL

Enrollment

300

Conditions

Patients Requiring Endotracheal Intubation and Invasive Mechanical Ventilation

Interventions

Invasive mechanical ventilationDEVICE

Invasive ventilation was performed to all eligible patients. When patients met predefined criteria, spontaneous breathing trial was performed. Given spontaneous breathing trial passed, patients were extubated; on the contrary, patients would continue to receive invasive ventilation. If patients had respiratory failure after extubation, reintubation and invasive ventilation were necessary.

Eligibility

Sex: ALLMin age: 18 Years

Medical Language ↔ Plain English

Inclusion Criteria: * Requiring endotracheal intubation and invasive mechanical ventilation Exclusion Criteria: * Duration of invasive mechanical ventilation \< 48 hours； * Presence of tracheostomy； * Presence of upper airway obstruction.

Locations (1)

Respiratory intensive care unit, Beijing Chao Yang Hospital Jingxi Campus

Beiling, China

RECRUITING

Outcomes

Primary Outcomes

Weaning failure rate

Time frame: 3.5 years

Spontaneous breathing trial failure rate

Time frame: 3.5 years

Extubation failure rate

Time frame: 3.5 years

Secondary Outcomes

ICU mortality

Time frame: 3.5 years

Hospital mortality

Time frame: 3.5 years

ICU length of stay

Time frame: 3.5 years

Hospital length of stay

Time frame: 3.5 years

Central Contacts

Zujin Luo, MD

CONTACT

xmjg2002@163.com

Data from ClinicalTrials.gov

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