The participant is being asked to be a subject in this research study because the participant may have a disorder that can cause optic nerve damage and impairment of his/her visual function which is called optic neuropathies (ON). Optic neuropathy refers to damage to the optic nerve (a "cable" connecting the eyes and the brain to transmit the visual signals) due to any cause.In this study, the investigator is using magnetic resonance imaging (MRI) and ophthalmic measures such as optic coherent tomography(OCT), which are non-invasive imaging tests to measure the changes in eye globe shape ,the flow of blood and brain fluid. It is hoped that this study will provide new knowledge that may allow the investigator to better understand the cause of symptoms associated with optic neuropathy and ways to better monitor what is happening.
Study Type
OBSERVATIONAL
Enrollment
10
Radiographic imaging that takes about 30-45 minutes
Images taken from the back of the eye (retina)
Bascom Palmer Eye Institute
Miami, Florida, United States
Globe deformation
Three measures of globe deformation are calculated by using the distance map: 1) optic nerve cupping(ONC), depicting the extent of the nerve head cupping; 2) posterior scleral bowing, depicting the degree of displacement of the posterior wall, and 3) maximal deformation (MD), depicting the combined deformation due to the displacement and the nerve cupping.
Time frame: day 1
intracranial pressure
Intracranial pressure will be measured using non invasive MRI.
Time frame: Day 1
Corneal thickness
Corneal thickness will be measured by corneal pachymetry. After anesthetic numbing drop is placed on the eye, blunt probe will briefly touch the participant's eye to obtain the measurement.
Time frame: Day 1
Visual field defect
Humphrey Field Analyzer II will be used to acquire the Mean deviation(MD).
Time frame: Day 1
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