TLIF is a popular lumbar fusion technique to perform interbody fusion. Pedicle screws providing initial stability have been developed to correct deformity, improve the rate of fusion and speed patient's postoperative recovery. Conventionally, bilateral pedicle screw fixation is a standard approach. Recently, studies have revealed that unilateral pedicle screw fixation provides equivalent clinical outcomes and fusion rates as compared with bilateral pedicle screw fixation in lumbar fusion. Meanwhile, the unilateral approach can reduce intraoperative blood loss and operating time. To our knowledge, few randomized controlled studies comparing unilateral versus bilateral instrumented TLIF in lumbar degenerative diseases have been reported. The purpose of this study is to compare clinical and radiographic outcomes in a series of patients with lumbar foraminal stenosis using instrumented TLIF with unilateral or bilateral pedicle screw fixation.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
NONE
Enrollment
53
TLIF combined with posterior unilateral pedicle screw fixation
TLIF combined with posterior bilateral pedicle screw fixation
Pedicle screw and cage
Department of Orthopedic Surgery, Shanghai Ninth People's Hospital
Shanghai, China
Visual Analogue Scale (VAS) scores
Time frame: 2 years postoperatively
Adverse events related to procedure
Time frame: 2 years postoperatively
Operative duration
Time frame: 1 week postoperatively
Estimated blood loss
Time frame: 1 week postoperatively
Length of hospital stay
Time frame: 1 week after discharge
Spinal angles
Radiographic parameters
Time frame: 2 years postoperatively
Intervertebral space height
Radiographic parameters
Time frame: 2 years postoperatively
Foraminal height
Radiographic parameters
Time frame: 2 years postoperatively
Cost of treatment
Time frame: 2 years postoperatively
Fusion rate
Time frame: 2 years postoperatively
Oswestry Disability Index (ODI)
Time frame: 2 years postoperatively
This platform is for informational purposes only and does not constitute medical advice. Always consult a qualified healthcare professional.