How Does Altering the Timing of Pre-exercise Low-dose Caffeine Ingestion Affect Endurance Exercise Performance

University of Exeter14 enrolled

Overview

Investigate how manipulating the time between caffeine ingestion and exercise may alter exercise performance and cognition

Study Type

INTERVENTIONAL

Allocation

RANDOMIZED

Purpose

BASIC_SCIENCE

Masking

TRIPLE

Enrollment

Conditions

Healthy

Interventions

Caffeine powder -60OTHER

Caffeine powder -30OTHER

Caffeine powder 0OTHER

Placebo powder -60OTHER

Eligibility

Sex: ALLMin age: 18 YearsMax age: 40 YearsHealthy volunteers:

Medical Language ↔ Plain English

Inclusion Criteria: * vo2max \> 55 ml/kg/min * females on contraceptive pill Exclusion Criteria: * recent skeletal muscle injury * cardiovascular injury * metabolic disease

Locations (1)

Sport and Health Sciences

Exeter, Devon, United Kingdom

Outcomes

Primary Outcomes

Work done in kilojoules (kJ) during a 15 minute time trial on a cycle ergometer

Time frame: 15 minutes

Secondary Outcomes

Whole body fuel substrate utilisation measured using indirect calorimetry

Time frame: 10 minutes

Change in plasma caffeine concentration and metabolites

Time frame: 2 hours 45 minutes

Change in cognitive function measured using stroop test

Time frame: 2 hours 45 minutes

Collection of saliva for genotyping of CYP1A2

Time frame: 30 mintes

Data from ClinicalTrials.gov

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