Multicenter Double-Blind Randomized Split-Face Study to Evaluate Revanesse® Ultra vs Restylane® for Correction of NLF

Inclusion Criteria: Subjects must meet all of the following criteria to be eligible for the study: 1. Men or women 22 years of age or older. 2. Two fully visible bilateral nasolabial folds each with a Wrinkle Severity Rating Scale Score of 3 or 4 that may be corrected with an injectable dermal filler. 3. If female and of childbearing potential, a negative urine pregnancy test and agree to use adequate contraception. Female subjects of childbearing potential (excluding women who are surgically sterilized or postmenopausal for at least 2 years) must have a negative urine pregnancy test and must be willing to use a medically accepted method of contraception during the study. The following are considered acceptable methods of birth control for the purpose of this study: oral contraceptives, contraceptive patches, contraceptive implant, vaginal contraceptive, double barrier methods (e.g., condom and spermicide), contraceptive injection (Depo-Provera®), intrauterine device (IUD), hormonal IUD (Mirena®), and abstinence with a documented second acceptable method of birth control if the subject becomes sexually active. Subjects entering the study who are on hormonal contraceptives must have been on the method for at least 90 days prior to the study and continue the method for the duration of the study. Subjects who had used hormonal contraception and stopped must have stopped no less than 90 days prior to Visit 1/Day 1. 4. Ability to understand and comply with the requirements of the study. 5. Willingness and ability to provide written informed consent. 6. Agree to refrain from seeking other treatment for this condition during the study. \- Exclusion Criteria: Subjects who meet any of the following criteria will be excluded from the study: 1. Wrinkle Severity Rating Scale Score of ≤ 2 on the right or left nasolabial fold. 2. Women who are pregnant or lactating. 3. Received prior dermabrasion, facelift, or Botox below the orbital rim within 6 months (180 days) prior to entry into the study. 4. Previous tissue augmentation (bulking agents) for facial wrinkles and scars within 6 months (180 days) at the proposed injection sites. 5. Previous tissue augmentation with permanent implants. 6. Evidence of scar-related disease or delayed healing activity within the past 1 year. 7. Scars at the intended treatment sites. 8. History of keloid formation or hypertrophic scars. 9. Any infection or wound on the face. 10. Allergic history including anaphylaxis or multiple severe allergies to natural rubber latex or lidocaine. 11. Aspirin or nonsteroidal anti-inflammatory drugs within 1 week (7 days) prior to treatment. 12. Concomitant anticoagulant therapy, antiplatelet therapy, or history of bleeding disorders or connective tissue disorders. 13. Over-the-counter (OTC) wrinkle products or prescription wrinkle treatments within 4 weeks (28 days) prior to treatment and throughout the study. 14. Immunocompromised or immunosuppressed. 15. Clinically significant organic disease including clinically significant cardiovascular, hepatic, pulmonary, neurologic, or renal disease or other medical condition, serious intercurrent illness, or extenuating circumstance that, in the opinion of the investigator, preclude participation in the trial. 16. Received any investigational product within 30 days of signing the Informed Consent Form. 17. Facial tattoo that may interfere with diagnosis. 18. Systemic (oral/injectable) corticosteroids or immunosuppressive medications within 30 days prior to treatment and topical steroids on the face within 14 days prior to treatment start and throughout the study. \-