Perioperative Immunonutrition in Colorectal Cancer Patients Undergoing Abdominal Surgery

Inclusion Criteria: * Patients with a diagnosis of a primary colorectal cancer and eligible for surgical resection. * Patients \> 18 years of age * Eligible patients must have signed a consent for surgical resection of the malignancy. * Ability to understand and provide a signed informed consent form (ICF) approved by the Research ethics board (REB). * Adequate kidney function with Creatine clearance\>30mL/min * Hemoglobin level \>90 mg/dL * Ability to comply with protocol requirements. Exclusion Criteria: * Prior adjuvant chemotherapy or radiation within 8 weeks of planned surgery. * Documented significant immunodeficiency due to underlying illness (e.g. HIV/AIDS) and/or medication (e.g. systemic corticosteroids, azathioprine, cyclosporin A). Subjects may be on physiologic doses of replacement prednisone or equivalent doses of corticosteroid (\<7.5 mg daily). * Subjects with resting hypotension (Blood pressure \<90/50 at rest). * History of autoimmune disease, such as but not restricted to, inflammatory bowel disease, systemic lupus erythematosus, ankylosing spondylitis, scleroderma, or multiple sclerosis. * Serious intercurrent chronic or acute illness, or other illness considered by the investigator as an unwarranted high risk for an investigational product. * Active infection of any site and/or active herpes requiring ongoing treatment * Known pregnancy or nursing mothers * Subjects with a fish allergy. * Subjects with severe asthma defined as asthma not controlled with inhaled corticosteroids and additional controllers or by oral corticosteroid treatment (arginine can cause allergic response or make swelling in airways worse). * Subjects with a known inherited guanidinoacetate methyltransferase deficiency (due to an inability to convert arginine to creatine) * Subject with known history of liver cirrhosis * Subjects who have who have suffered a myocardial infarction or life-threatening arrhythmia within the last 6 months * Subjects with cardiac failure or coronary artery disease causing unstable angina * Subjects with a medical or psychological impediment to probable compliance with the protocol should be excluded.