A feasibility and pilot trial to investigate the feasibility of a newly manualized psychotherapy "Mentalization-Based Training for Adolescents with Conduct Disorder (MBT-CD)"
Background: Conduct Disorder is a severe and complex mental disorder with the highest incidence in adolescence. Previous studies have shown that family-oriented interventions are effective in the treatment of Conduct Disorder. However, most therapies focus rather on symptom management and less on etiological causes without inclusion of the family in the therapeutic process. Previous research has linked specific symptoms of Conduct Disorder with deficits in mentalization ability. Mentalization is the ability to perceive one's own and other's behavior as the product of affective and cognitive mental states. Low or missing mentalization abilities are regarded as a risk factor for the development and chronification of Conduct Disorder. Aims: The study aims to investigate the feasibility of a newly manualized psychotherapy "Mentalization-Based Training for Adolescents with Conduct Disorder (MBT-CD)" that strives to decrease symptoms associated with Conduct Disorder by increasing mentalization in adolescents and their families. Methods: The study is feasibility and piolot trial, carried out in Heidelberg (Germany), and Mainz (Germany). Adolescents aged between 11-18, who meet the DSM-5 criteria for Conduct Disorder will receive MBT-CD. Times of measurement: t0 (Screening), T1 (Baseline, at the beginning of therapy), T2 (3 months after the beginning of therapy), T3 (at the end of therapy, after 6 months), T4 (follow-up, after 9 months).
Study Type
INTERVENTIONAL
Allocation
NA
Purpose
TREATMENT
Masking
NONE
Enrollment
45
MBT-CD is a disorder-specific modification of MBT, initially developed for patients with Borderline Personality Disorder. It is a manualized and psychodynamically oriented psychotherapy with the aim to increase the mentalization capacity of adolescents in close relationships. The therapy consists of 2 psychoeducational group sessions, 30 individual therapy sessions and 10 family sessions. The average duration of therapy is 6 months.
Heidelberg University
Heidelberg, Germany
Structured Clinical Interview for DSM-IV Axis II Disorders (SCID-II)
Time frame: Change from baseline in SCID-II at 12 months (at the end of therapy)
Subtypes of Antisocial Behaviour Questionnaire (STAB)
Time frame: Change from baseline in STAB at 6 months
Subtypes of Antisocial Behaviour Questionnaire (STAB)
Time frame: Change from baseline in STAB at 12 months (at the end of therapy)
Subtypes of Antisocial Behaviour Questionnaire (STAB)
Time frame: Change from baseline in STAB at 18 months (follow-up)
Reactive-Proactive-Aggression Questionnaire (RPQ)
Time frame: Change from baseline in RPQ at 6 months
Reactive-Proactive-Aggression Questionnaire (RPQ)
Time frame: Change from baseline in RPQ at 12 months (at the end of therapy)
Reactive-Proactive-Aggression Questionnaire (RPQ)
Time frame: Change from baseline in RPQ at 18 months (follow-up)
Global Assessment of Functioning (GAF)
Time frame: Change from baseline in GAF at 12 months (at the end of therapy)
Clinical Global Impression (CGI-SI)
Time frame: Change from baseline in CGI-SI at 12 months (at the end of therapy)
Levels of Personality Functioning - Questionnaire Adolescence (LoPF-QA)
Time frame: Change from baseline in LoPF-QA at 12 months (at the end of therapy)
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Levels of Personality Functioning - Questionnaire Adolescence (LoPF-QA)
Time frame: Change from baseline in LoPF-QA at 18 months (follow-up)
Reflective Functioning Questionnaire (RFQ)
Time frame: Change from baseline in RFQ at 12 months (at the end of therapy)
Reflective Functioning Questionnaire (RFQ)
Time frame: Change from baseline in RFQ at 18 months (follow-up)
Movie for the Assessment of Social Cognition (MASC)
Time frame: Change from baseline in MASC at 12 months (at the end of therapy)
10 round Trust Game Task (TGT)
Time frame: Change from baseline in TGT at 12 months (at the end of therapy)
Social Hierarchy Task (SHT)
Time frame: Change from baseline in SHT at 12 months (at the end of therapy)
Approach-Avoidance Task (AAT)
Time frame: Change from baseline in AAT at 12 months (at the end of therapy)
Symptom Checklist-90-Revised (SCL-90R)
Time frame: Change from baseline in SCL-90R at 12 months (at the end of therapy)
Stress Index for Parents of Adolescents (SIPA)
Time frame: Change from baseline in SIPA at 12 months (at the end of therapy)
Stress Index for Parents of Adolescents (SIPA)
Time frame: Change from baseline in SIPA at 18 months (follow-up)
drop-out rates
Time frame: after 12 months (at the end of therapy)
cost-effectiveness
Cost-effectiveness will be measured by participation in training/school, rehospitalization, internment
Time frame: after 12 months (at the end of therapy)