Bipolar disorder is a major health concern. Intercritical periods are marked with residual symptoms, both thymic and cognitive, which affects quality of life of patients, but also the quality of observance. The implementation of cognitive remediation programs could be interesting. The aim of this study is to evaluate the overall performance on euthymic bipolar patients with memory complaints included in the program named "COGMED", targeting the working memory. The impact of this program on compliance, quality of life, and memory complaints will be evaluated. The investigator will measure whether there is a correlation between working memory and overall performances. Finally, the investigator will try to achieve a profile of bipolar patients in whom the Cogmed program is particularly effective on a plan of overall performance.
Patients with bipolar disorder and memory complaints will be recruited. Two visits : 1. at baseline (V0) : the investigator evaluate bipolar disorder, treatment, mood, quality of life, global functioning, and memory complaints. Patients also have a neuropsychological assessment. The COGMED program is proposed to patients with memory complaints and explain by the investigator 2. 4-6 weeks after the end of the program (11-13 weeks after V1) : the same evaluation is realized to compare score before and after the program of cognitive remediation. Between the two visits the patient will benefit of COGMED program, at home, during 5 weeks. COGMED is a remediation cognitive program, based on working memory, consisting on daily exercises at home on a computer.
Study Type
INTERVENTIONAL
Allocation
NA
Purpose
SUPPORTIVE_CARE
Masking
NONE
Enrollment
41
Patient should connect on his computer at home, 5 times a week, for 5 weeks. Every day, the patient has to do 8 exercises for a total duration of 30 to 45 minutes. In total, the patient will have to complete 25 sessions. The difficulty level of the proposed items adjust automatically to the patient's maximum capacity to compel him to provide a cognitive effort. A progression index assesses the progress made by the patient. Every week, the investigator will call the patient for 10 minutes in order to gather the patient's feelings, his difficulties, provide some advice and encourage him. The investigator will have to analyze the results of curves available for each event, as well as the patient's progress index.
Montpellier University Hospital
Montpellier, France
RECRUITINGEvolution of the global functioning between the inclusion and the end of the program
evaluation of variation of global functioning will be realized by the Functioning Assessment Short Test (FAST) scale after COGMED program.
Time frame: At 4 weeks
Evolution of the global functioning between the inclusion and the end of the program
evaluation of variation of global functioning will be realized by the Functioning Assessment Short Test (FAST) scale after COGMED program
Time frame: At 6 weeks
Observance
Evaluation of variation of patient's compliance by Medication Adherence Rating Scale (MARS) score after COGMED program.
Time frame: At the inclusion and 4 to 6 weeks until the end of the program COGMED (11 to 13 weeks after inclusion)
Quality of life
Evaluation of variation of quality of life by Short Form (36) Health Survey (SF-36) score after COGMED program.
Time frame: At the inclusion and 4 to 6 weeks until the end of the program COGMED (11 to 13 weeks after inclusion)
Correlation between working memory and global functioning
Searching a statistical correlation between global functioning (using FAST) and working memory (using neuropsychological tests)
Time frame: At the inclusion and 4 to 6 weeks until the end of the program COGMED (11 to 13 weeks after inclusion)
Memory complaints
Variations on memory complaints will be evaluated by Mac Nair Scale score before and after COGMED program.
Time frame: At the inclusion and 4 to 6 weeks until the end of the program COGMED (11 to 13 weeks after inclusion)
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