This pilot phase I trial studies how well copper Cu 64 TP3805 positron emission tomography (PET) works in detecting prostate cancer in patients with persistently elevated prostate specific antigen (PSA). The copper Cu 64 TP3805 PET scan uses copper Cu 64 TP3805, a compound made of a radioactive agent attached to a molecule that looks like a hormone that binds to cancer cells to detect prostate cancer during PET scans. Copper Cu 64 TP3805 PET may be able to see tumors at an earlier stage than the standard of care.
PRIMARY OBJECTIVES: I. To assess the ability of Cu-64-TP3805 (copper Cu 64 TP3805) to detect prostate cancer (PC), or absence thereof, within the prostate gland.
Study Type
INTERVENTIONAL
Allocation
NA
Purpose
DIAGNOSTIC
Masking
NONE
Enrollment
25
Given Intravenously
Undergo copper Cu 64 TP3805 PET/CT scan
Thomas Jefferson University
Philadelphia, Pennsylvania, United States
Prostate Cancer Detection Within the Prostate Gland by Copper Cu 64 TP3805 PET
The proportion of participants with lesions detected with copper Cu-64 PET will be determined with the lesion as the unit of analysis. 95% confidence intervals will be calculated.
Time frame: At 3 weeks post imaging visit
Total Incidence of Multiple Lesions in an Individual Patient
Generalized Estimating Equations will be utilized to provide a total number of lesions
Time frame: At 3 weeks post imaging procedure
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