The Impact of the Timing of Trigger on IVF Success

Colorado Center for Reproductive Medicine29 enrolled

Overview

The aim of this study is to examine the length of ovarian stimulation with the timing of trigger in an IVF cycle and its potential to impact patient outcomes.

Study Type

INTERVENTIONAL

Allocation

RANDOMIZED

Purpose

TREATMENT

Masking

NONE

Enrollment

Conditions

Fertilization in Vitro Infertility Embryonic Development

Interventions

Timing of triggerOTHER

Eligibility

Sex: FEMALEMin age: 26 YearsMax age: 44 YearsHealthy volunteers:

Medical Language ↔ Plain English

Inclusion Criteria: * Planning to move forward with an IVF cycle * Have met the requirements of being a patient at CCRM Colorado * AMA: 39-44 years old And/or * DOR: AMH \< 1 \& FSH \>10 (age independent) Exclusion Criteria: * Contraindication for pregnancy * Have not fulfilled requirements for IVF cycle * Single gene couple or chromosomal rearrangement * Severe male factor or testicular surgical sperm removal (need sufficient sperm for ICSI) * One ovary * Uterine anomalies * Stage III or IV endometriosis * Explained recurrent miscarriage * PCO or PCOS * Using donor oocyte or gestational carrier

Locations (1)

Colorado Center for Reproductive Medicine

Lone Tree, Colorado, United States

Outcomes

Primary Outcomes

Euploid Embryos: the percentage of euploid embryos produced as analyzed by comprehensive chromosomal screening, of total embryos tested

Time frame: 4 weeks after egg retrieval

Secondary Outcomes

Egg maturation: the proportion of mature eggs of total number of eggs retrieved

Time frame: 1 week after egg retrieval

Live birth outcomes: the incidence of pregnancy resulting in live birth following embryo transfer of embryos produced by this IVF cycle

Time frame: 9 months after frozen embryo transfer

Data from ClinicalTrials.gov

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