Exercise Effect on Chemotherapy-Induced Neuropathic Pain

Inclusion Criteria: * Diagnosis with cancer, stage I-IV * History of treatment with oxaliplatin, docetaxel, or paclitaxel, either alone or in combination with other agents * Completion of chemotherapy \> 6 months \< 1 year * Ability to walk on a treadmill * Medical clearance from oncologist or primary care provider * Presence of CIPN per National Cancer Institute Common Toxicity Criteria grade 1-3 (0-no signs/symptoms, 1-minor loss of function, 2-increased symptoms not interfering with activities of daily living (ADLs), 3-severe symptoms interfering with ADL, 4-disabling, and 5 is death) * Score on Neuropathic Pain Scale \>1 * Age 21-70 Exclusion Criteria: * Denial of CIPN * Other motor/sensory neuropathy caused by other than chemotherapy (i.e.alcohol-related, autoimmune diseases, diabetes) * Coronary artery disease * History of \>1 chemotherapy regimen * Musculoskeletal conditions which preclude participation in an exercise training program * Pregnancy * Regular exerciser, defined as \>90 minutes per week of aerobic exercise and any resistive training