The purpose of this study is to investigate risk factors for mediastinal lymph node metastasis in potentially operable non-small cell lung cancer in order to find indications for endoscopic mediastinal staging. Chest CT, integrated PET/CT, and endobronchial ultrasound guided transbronchial needle aspiration (EBUS-TBNA) +/- endoscopic ultrasound with bronchoscope-guided fine needle aspiration (EUS-B-FNA) are performed for mediastinal staging. CT and PET/CT findings, histologic types and other risk factors will be analyzed. The investigators develop the prediction method for mediastinal metastasis.
Study Type
OBSERVATIONAL
Enrollment
600
National Cancer Center (NCC) Korea
Goyang-si, Gyeonggi-do, South Korea
Relative risk of risk factors for mediastinal metastasis
risk factors; CT staging (N0-3), PET staging (N0-3), tumor location(central or peripheral), tumor size and histologic types of lung cancer.
Time frame: When confirmative diagnosis are available in all subjects ;3 years
Diagnostic values of endoscopic staging
sensitivity, negative predictive value, accuracy
Time frame: When confirmative diagnosis are available in all subjects ;3 years
Survival
survival after lung cancer treatment
Time frame: After the diagnosis ; 7 years
Molecular test
EGFR, ALK etc
Time frame: for each subject; up to 60 days, available in all subjects ; 3 years
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