Assisted reproduction patients candidates to an IVF/ICSI cycle with low follicular reserve: after at least one cycle of stimulation obtaining 0-4 oocytes. Improve the follicular response in patients with low response, increasing the number of follicles in subsequent cycles to treatment with growth factors.
Study Type
INTERVENTIONAL
Allocation
NA
Purpose
TREATMENT
Masking
NONE
Enrollment
51
one dose 3-6 mL of PRP obtained by PRGF Endoret
IVI Bilbao
Leioa, Vizcaya, Spain
Number of follicles recruited after instability of ovarian growth factors
o demonstrate an increase of at least 20% in the number of MII oocytes in a cycle after IVF/ICSI treatment with PRGF®-Endoret® compared to previous cycles in low IVF/ICSI patients. IVF/ICSI treatment with PRGF®-Endoret® with respect to previous cycles in low responders. responders
Time frame: two months; Time included in two protocols of ovarian stimulation
Rates of pregnancy rates
Increase pregnancy rates and decrease the number of cycles of accumulation of oocytes.
Time frame: three months after embryo transfer after treatment of growth factors
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