"Natural History" Study of Choroideremia

Inclusion Criteria (Primary Cohort): * Healthy individuals (at least 14 years) with choroideremia (20/200 or better vision) willing to participate in an observational study and meeting the eligibility criteria. Inclusion Criteria (Expansion Cohort): * Healthy individuals (at least 18 years) with choroideremia (20/200 or better vision in both eyes) willing to participate in an observational study and meeting the eligibility criteria. Exclusion Criteria (Primary and Expansion Cohort): 1. Prior therapy with an AAV vector-based treatment 2. Pre-existing eye conditions that would: (1) preclude future planned treatment in a therapeutic intent clinical trial (i.e. intravitreal injection), (2) interfere with the interpretation of study endpoints, and/ or put patient at risk for surgical complications 3. Complicating systemic diseases that would preclude future enrollment in a therapeutic intent clinical trial 4. Any other condition that would not allow the potential subject to complete follow-up examinations during the course of the study and, in the opinion of the investigator, makes the potential subject unsuitable for the study.