The purpose of this study is to investigates serum and stool biomarkers as predictors for post-operative feeding intolerance in infant patients with complex congenital heart defects who undergo single ventricle staged palliation surgery.
Study Type
OBSERVATIONAL
Enrollment
30
The University of Texas Health Science Center at Houston
Houston, Texas, United States
RECRUITINGLevel of most abundant serum protein as determined by ELISA
We will select two proteins with top changes that are involved in the pathways for intestinal inflammation, and levels will be determined with either ELISA or other techniques that are available.
Time frame: baseline (3-5 days after initial cardiac surgery), within three weeks of the initial cardiac surgery
Level of second most abundant serum protein as determined by ELISA
Time frame: baseline (3-5 days after initial cardiac surgery), within three weeks of the initial cardiac surgery
Level of stool biomarker interleukin-8 (IL-8) as determined by ELISA
Time frame: baseline (3-5 days after initial cardiac surgery), within three weeks of the initial cardiac surgery
Level of stool biomarker calprotectin as determined by ELISA
Time frame: baseline (3-5 days after initial cardiac surgery), within three weeks of the initial cardiac surgery
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