He-Mu-point combination(ST36 and CV12) is one of the most commonly used acupoints combination with synergistic effect for functional dyspepsia(FD). The investigators design the trial to identify the efficacy and explore the central integrated mechanism of puncturing at He-Mu-point combination on FD with functional magnetic resonance imaging (fMRI).
105 participants with functional dyspepsia will be allocated into three groups: Low-He point group, Mu point group and He-Mu-point combination group.Every participant will receive 20 sessions of manual acupuncture treatment during 4 weeks. Clinical evaluations will be assessed three times, as measured after randomization, 10 and 20 sessions of treatment.The fMRI scans will be conducted twice, after randomization and treatment completion.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
DOUBLE
Enrollment
105
Manual acupuncture treatment will be conducted. thirty minutes duration every time, five times per week for one course, a total four courses.
Chengdu University of Traditional Chinese Medicine
Chengdu, Sichuan, China
Nepean Dyspepsia Index (NDI)
Time frame: 4 weeks after allocation
Self-Rating Anxiety Scale
Time frame: 0 day,2, 4weeks after allocation
Self-Rating Depression Scale
Time frame: 0 day,2, 4weeks after allocation
Leeds dyspepsia questionnaire
Time frame: 0 day,4 weeks after allocation
brain MRI data
Time frame: 0 day,4weeks after allocation
The incidence of adverse events during the 4 weeks
Time frame: 4weeks after allocation
This platform is for informational purposes only and does not constitute medical advice. Always consult a qualified healthcare professional.