Door To Unloading With IMPELLA CP System in Acute Myocardial Infarction - Safety and Feasibility Study

Main Inclusion Criteria: * Age 21-80 years * First myocardial infarction * Acute anterior STEMI with ≥ 2 mm in 2 or more contiguous anterior leads or≥ 4 mm total ST-segment deviation sum in the anterior leads * Signed Informed Consent Main Exclusion Criteria: * Cardiogenic shock defined as: systemic hypotension (systolic BP less than 90 mmHg or the need for inotropes/pressors to maintain a systolic BP Greater than 90mmHg) plus one of the following: any requirement for pressors/inotropes prior to arrival at the cath lab, clinical evidence of end organ hypoperfusion, lactate level greater than 2.5mmol/L * Inferior STEMI or suspected right ventricular failure * Suspected or known pregnancy * Suspected active infection * History or known hepatic insufficiency prior to catheterization * On dialysis therapy * Known contraindication to: * Undergoing MRI or use of gadolinium * Heparin, pork, pork products or contrast media * Receiving a drug-eluting stent * Participation in the active treatment or follow-up phase of another clinical study of an investigational drug or device