S1P1 Receptor Subtype (S1PR1) Axis in Patients With Interstitial Cystitis (IC) Pain

St. Louis University21 enrolled

Overview

For each patient in the study, blood, and pain scores will be collected to look for markers for pain, at the start of treatment and 6 months after surgery of treatment.

The study is investigator-initiated, prospective, study. There will be no change in care. Patients who have had a diagnosis of IC made by cystoscopy and hydrodistension and still have pain will be recruited for this study. Patients will have blood samples taken at the visit they sign the consent form and 6 months later. The study staff will call and remind the patient of their 6 month visit.

Study Type

OBSERVATIONAL

Enrollment

Conditions

Interstitial Cystitis

Interventions

QuestionnairesOTHER

QOL and pain questionnaires will be given to patients at 3, 6, and 12 months post surgery

Collection of Blood samplesOTHER

Blood for PBLs will be collected at 3, 6, and 12 months post surgery

Eligibility

Sex: FEMALEMin age: 18 YearsMax age: 70 Years

Medical Language ↔ Plain English

Inclusion Criteria: * 18-70 years of age * Patients must be able to provide written informed consent. * Diagnosis of Interstitial Cystitis documented by provider Exclusion Criteria: * age \<18 or \>70 years of age * pregnant

Locations (1)

Saint Louis University Department of Obstetrics, Gynecology, and Women's Health

St Louis, Missouri, United States

Outcomes

Primary Outcomes

Change From Baseline in Pain Scores on the Visual Analog Scale at 6 months

S1PR1 levels in PBLs can discriminate patients with Interstitial Cystitis pain and patients with other types of pain.

Time frame: 3 months

Data from ClinicalTrials.gov

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