StrataGraft® Skin Tissue in the Promotion of Autologous Skin Regeneration of Complex Skin Defects Due to Thermal Burns That Contain Intact Dermal Elements

Inclusion Criteria Subject-specific criteria: 1. Men and women aged ≥ 18 years 2. Written informed consent 3. Sufficient healthy skin identified and reserved as a donor site in the event that the StrataGraft treatment site requires autografting 4. Clinical expectation that the study donor site will heal without grafting 5. Complex skin defects of 3-49% TBSA * Total burn may consist of more than one area Treatment site-specific criteria: 6. Thermal burn(s) with intact dermal elements for which excision and autografting are clinically indicated 7. Total of both study treatment areas can be up to 2000 cm2 8. First excision and grafting of study treatment sites 9. Thermal burn(s) on the torso, arms, or legs Exclusion Criteria Subject-specific criteria: 1. Pregnant women 2. Prisoners 3. Subjects receiving systemic immunosuppressive therapy 4. Subjects with a known history of malignancy 5. Preadmission insulin-dependent diabetic subjects 6. Subjects with concurrent conditions that in the opinion of the investigator may compromise subject safety or study objectives 7. Expected survival of less than three months 8. Participation in the treatment group of an interventional study within 90 days prior to enrollment Treatment site-specific criteria: 9. Full-thickness burns 10. Chronic wounds 11. The face, head, neck, hands, feet, buttocks, and area over joints 12. Treatment sites immediately adjacent to unexcised eschar 13. Clinical or laboratory determination of infection at the anticipated treatment sites