Integrative analysis of GBM
The investigators will analyzed proteomes of paired normal brain tissues and GBM, sequenced transcriptomes, perform whole exome sequencing, and single nucleotide polymorphism (SNP) array profiling for triplets, each comprising normal brain tissue, primary GBM carcinoma, and its synchronous matched metastasis, as well as analyzed genomics of GBM characterized previously by The Cancer Genome Atlas (TCGA) to conduct integrated proteogenomic analyses.
Study Type
OBSERVATIONAL
Enrollment
1,000
The investigators will extract total protein, DNA and RNA from the samples.
Shanghai Tenth People's Hospital
Shanghai, Shanghai Municipality, China
RECRUITING5 years overall survival
Time frame: 5 years
5 years disease-free survival
Time frame: 5 years
10 years overall survival
Time frame: 10 years
10 years disease-free survival
Time frame: 10 years
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