Treatment of Candidal Vulvovaginitis Using Cumin Seed Extract Vaginal Suppositories.

Assiut University100 enrolled

Overview

Fungal infections have increased over the last two decades, largely because of the increasing size of the population at risk, including patients who are immunocompromised, broad-spectrum antibiotics and intravascular catheter users. Essential oils and other extracts of plants have evoked interest as sources of natural products. They have been shown to possess antibacterial, antifungal, antiviral, insecticidal and antioxidant properties. To the best of our knowledge, no study has examined the efficacy of cumin seed extract on relieving vulvovaginal candidiasis in vivo.

Study Type

INTERVENTIONAL

Allocation

RANDOMIZED

Purpose

TREATMENT

Masking

TRIPLE

Enrollment

100

Conditions

Infection, Fungal

Interventions

Cumin seed extractDRUG

patients will receive the drug in suppository form

clotrimazoleDRUG

patients will receive the drug in suppository form

Eligibility

Sex: FEMALEMin age: 18 YearsMax age: 49 Years

Medical Language ↔ Plain English

Inclusion Criteria: 1. Women were 18-49 years old and were married; 2. They had not used antibiotics, immunosuppressive drugs, or vaginal drugs 14 days before the study; 3. They did not suffer from trichomonal vaginitis, bacterial vaginitis, or cervicitis based on direct smear; 4. Candidiasis culture was in agreement with clinical symptoms and patient's complaints. Exclusion Criteria: 1. Pregnant and lactating women; 2. Those who had abnormal uterine bleeding; 3. Women with diabetes or autoimmune diseases; 4. Women refuse to participate in the study.

Locations (1)

Assiut University

Asyut, Egypt

Outcomes

Primary Outcomes

The percentage of patients with complete cure

cure is defines as absence of symptoms

Time frame: one week

Data from ClinicalTrials.gov

This platform is for informational purposes only and does not constitute medical advice. Always consult a qualified healthcare professional.