To evaluate the mean changes in Endothelial Cell and Corneal pachymetry in eyes that operated under N2O + sevoflurane and O2 + sevoflurane general anesthesia.
40 eyes of 40 patients who had extraocular surgery under general anesthesia will be included in this prospective study. Cell density, Cell variatio, Hexagonality rate and pachymetry specular microscopy results at before surgery and 1 week and 1 month after surgery will be analyzed. O2 (1 l/min) with 50% air and N2O (1 l/min) with 50% air will be applied to each group with flow rate 2 l/min totally, respectively. The duration of surgery will be recorded.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
OTHER
Masking
SINGLE
Enrollment
40
Change of corneal endothal number
Nitrogen protoxide and oxygen may be change this number
Time frame: after surgery at first day, 1th week and 1th month
Change of Cell density rate
Nitrogen protoxide and oxygen may be change this rate
Time frame: after surgery at first day, 1th week and 1th month
Change of Cell variation rate
Nitrogen protoxide and oxygen may be change this rate
Time frame: at before surgery and 1 week and 1 month after surgery
Change of Hexagonality rate
Nitrogen protoxide and oxygen may be change this rate
Time frame: after surgery at first day, 1th week and 1th month
Change of pachymetry specular microscopy results
Nitrogen protoxide and oxygen may be change these results
Time frame: after surgery at first day, 1th week and 1th month
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