Peripheral Perfusion Index (PPI) as Monitor During Deliberate Hypotensive Anesthesia

Cairo University50 enrolled

Overview

Hypotensive anesthesia is effective in reducing the intraoperative blood loss. The risk of hypoperfusion of vital organs continues to be a concern. An adequate monitoring of tissue perfusion and oxygenation is crucial issue. Peripheral Perfusion Index (PPI) as a noninvasive new monitoring, can reflect the peripheral perfusion dynamics. This study is designed to explore the behaviour and trend of PPI during nitroglycerine induced deliberate hypotensive anesthesia in adult patients undergoing functional endoscopic sinus surgery (FESS).

Study Type

OBSERVATIONAL

Enrollment

Conditions

Monitoring During Deliberate Hypotensive Anesthesia

Interventions

peripheral perfusion index measurementOTHER

Eligibility

Sex: ALLMin age: 18 YearsMax age: 50 Years

Medical Language ↔ Plain English

Inclusion Criteria: * Patients, aged from 18-50 years, ASA physical status I and II, undergoing functional endoscopic sinus surgery (FESS) under deliberate hypotensive anesthesia Exclusion Criteria: * Patients with systemic hypertension, cardiovascular disease, cerebrovascular insufficiency, coagulation defects, renal or hepatic insufficiency, and hypersensitivity to the study drugs will be excluded from the study. Patients receiving vasoactive drugs or beta blockers will be also excluded from the study.

Outcomes

Primary Outcomes

correlation between PPI and T1

correlation of baseline values of PPI and time required to achieve target mean arterial pressure.

Time frame: start of nitroglyceirn infusion till target arterial pressure is reached up to 2 hours

Data from ClinicalTrials.gov

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