This study aims to conduct a contrast study on the characteristics of functional and structural connectivity of neural networks of working memory in patients with acquired brain injury versus normal controls, using resting-state functional connectivity magnetic resonance imaging, task-specific functional magnetic resonance imaging and diffusion tensor imaging, combined with cognitive behavioral examinations. Another purpose is to reveal the characteristics of dynamic change of neural networks of working memory pre- and post-intervention in patients with working memory dysfunction.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
TRIPLE
Enrollment
40
Department of Rehabilitation Evaluation, China Rehabilitation Research Center
Beijing, Beijing Municipality, China
RECRUITINGTraining-induced brain activations during working memory tasks in fMRI
Training-induced increased and decreased brain activations (Number of voxels) during n-back verbal WM task compared to the pre-training baseline
Time frame: six weeks
The fluid intelligence measured by Raven's Standard Progressive Matrices (RSPM) test
Time frame: six weeks
Attention ability assessed by Stroop color-word test
Time frame: six weeks
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