Posterior Maxillary Ridge Augmentation With Sinus Lift Using Mineralized Plasmatic Matrix Versus Autogenous Bone Graft

Cairo University20 enrolled

Overview

Using growth factors obtained from patient's venous blood mixed with particulate autogenous bone the study compares bone gain by implant with gold standards in sinus Lift procedures for future implant insertion.

To study the effectiveness of MPM in ridge augmentation with implant insertion compared with autogenous bone graft. -PICO Population(P) : Patients with defective posterior maxillary alveolar ridge. Intervention (I) :Implant placement and ridge augmentation with MPM. Comparator (C) : Autogenous bone graft. Outcome (O) : Patient satisfaction - Implant stability.

Study Type

INTERVENTIONAL

Allocation

RANDOMIZED

Purpose

TREATMENT

Masking

DOUBLE

Enrollment

Conditions

Bone Resorption

Interventions

autogenous boneOTHER

Autogenous bone graft (gold standard). sinus lift with autogenous bone.

Mineralized plasmatic matrixOTHER

By using venoud blood from the patient, together with bone graft, a centrifuge will be used to obtain the top layer after centrifuging blood at 3000 RPM.

Eligibility

Sex: ALLMin age: 18 YearsMax age: 50 YearsHealthy volunteers:

Medical Language ↔ Plain English

Inclusion Criteria: 1. Patients systemically free. 2. Patients with posterior maxillary defective ridges indicated for sinus lift procedure. 3. Cases with 5 mm bone height or less are included in the study. 4. Age between 18 and 50 years. 5. Both sexes. 6. Patients physically able to tolerate surgical and restorative procedures. 7. Good oral hygiene. 8. Highly motivated patients. Exclusion Criteria: 1. Patients allergic to local anesthetic agent. 2. Medium and heavy smokers. 3. Pregnant females. 4. Presence of any pathosis in the pre-implant site. 5. Presence of any mucosal disease. 6. History of oral radiotherapy. 7. History of prolonged steroids use. 8. Psychological disorders.

Outcomes

Primary Outcomes

Patient Satisfaction regarding aesthetic results will be measured using questionnaire.

outcome will be measure using questionnaire.

Time frame: 9 months

Secondary Outcomes

Stability of dental implants.

will be measured using OSTELL Device.

Time frame: 5 months

Central Contacts

refaat ragab, Master

CONTACT

01111175536 refaat.ragab.rr@gmail.com

Data from ClinicalTrials.gov

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