Turmeric for Patients With Basal Joint Arthritis

Massachusetts General Hospital60 enrolled

Overview

The aim of this study is to assess whether the use of a commercially available nutraceutical, turmeric, is an effective option to manage pain and stiffness in patients with basal joint arthritis. To conduct a pilot Randomized Controlled Trial evaluating the impact of turmeric on basal joint arthritis.

Study Type

INTERVENTIONAL

Allocation

RANDOMIZED

Purpose

TREATMENT

Masking

QUADRUPLE

Enrollment

Conditions

Thumb Osteoarthritis

Interventions

TurmericDIETARY_SUPPLEMENT

Subjects will receive turmeric (100 mg pastille) 3 times per day for 6 weeks.

PlaceboOTHER

Subjects in the control group will receive a placebo 3 times per day for 6 weeks.

Eligibility

Sex: ALLMin age: 40 Years

Medical Language ↔ Plain English

Inclusion Criteria: * 40 years of age or older * English fluency and literacy * Seeking care for basal joint pain * Tender over basal joint * Positive distraction rotation test (rotation of the thumb metacarpal base while applying axial traction) * Radiographic evidence of Eaton stage 1 and 2 only Exclusion Criteria: * Secondary gains (litigations or worker compensation) procedures that may interfere with patients' motivation for treatment * Inability or unwillingness to participate in a trial study * Rheumatoid Arthritis or other inflammatory disorder diagnoses * Post-traumatic osteoarthritis * Patients on Coumadin/Steroids/NSAIDs/Tylenol * Diabetes Mellitus * Pregnant or lactating women * Basal joint arthritis of Eaton stage 3 * Patients seeking other treatment for their basal joint arthritis (splint, corticosteroid injection, surgery)

Locations (1)

Massachusetts General Hospital

Boston, Massachusetts, United States

RECRUITING

Outcomes

Primary Outcomes

Change in baseline pain intensity

0-10 ordinal rating of pain intensity

Time frame: Enrollment, 6 weeks, and 3 months

Change in baseline disability

Disability measured by the QuickDASH

Time frame: Enrollment, 6 weeks, and 3 months

Central Contacts

Neal Chen, M.D.

CONTACT

617-726-4700 nchen1@mgh.harvard.edu

Karan Amin, BA

CONTACT

kamin2@mgh.harvard.edu

Data from ClinicalTrials.gov

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