Observational Study With Mode of Action-Analysis of Cystorenal Cranberry Extract in Patients With Recurrent Urinary Tract Infections

N/ACompletedNCT03019874

Charite University, Berlin, Germany23 enrolled

Overview

The main focus of this observational study is to analyze the possible effects of cranberry dietary supplements on the intestinal microbiota in women with recurrent uncomplicated urinary tract infections. In a secondary analysis the possible influence of the microbiota changes on the recurrence frequency in the follow-up should be analyzed.

Study Type

OBSERVATIONAL

Enrollment

Conditions

Urinary Tract Infections

Interventions

Cranberry ExtractDIETARY_SUPPLEMENT

3 x Cystorenal Cranberry plus daily for 6 months (contains 300 mg Cranberry-Extract, 100 mg Pumpkin seeds-Extract, 20 mg Vitamin C und 0,47 mg Riboflavin)

Eligibility

Sex: FEMALEMin age: 18 YearsMax age: 70 Years

Medical Language ↔ Plain English

Inclusion criteria: • chronic recurrent urinary tract infections (≥3 infections per year or 2 infections in the last 6 months) Exclusion Criteria: * renal insufficiency (GFR \<60), * anatomical or known structural causes of urinary tract infections * regular consumption of probiotics or probiotic yogurts (at least 5x / week) * intake of antibiotics in the last 4 weeks * intake of Marcumar * simultaneous participation in another study

Locations (1)

Charité Hochschulambulanz für Naturheilkunde am Immanuel Krankenhaus

Berlin, Germany

Outcomes

Primary Outcomes

Number of urinary tract infections

Time frame: In the 6-month prospective observation period compared to a 6-month retrospective period

Secondary Outcomes

Quality of life (SF-36)

Time frame: Baseline, 4 weeks, 8 weeks, 6 months

Data from ClinicalTrials.gov

This platform is for informational purposes only and does not constitute medical advice. Always consult a qualified healthcare professional.