Efficacy and Safety of Danoprevir/r + PR 12-week Triple Therapy in Treatment-Naive, Non-Cirrhotic, G1 CHC China II

Inclusion Criteria: * Willing and able to provide written informed consent * Chronic HCV infection (≥ 6 months) ; * Positive HCV antibody * Serum HCV RNA of ≥ 1 × 104 IU/mL * Hepatitis C virus GT1 * Never received prior-treatment for HCV with interferon, RBV, or other direct-acting or host-targeting antivirals for HCV * The liver biopsy methods in the protocol (non-cirrhosis is defined as: Metavir score ˂ 4), or as determined by Fibroscan defined as: ˂ 14.6 kPa. Patients who have not obtained a liver biopsy or Fibroscan in the last 1 years will have a study related Fibroscan performed in order to confirm the diagnosis * Others as specified in the detailed protocol Exclusion Criteria: * Patients with Fibroscan detection value \> 12.9 kPa, or histologic examination for liver cirrhosis patients * Presence or history of non-hepatitis C chronic liver disease, including but not limited to, autoimmune hepatitis, α-1-antitrypsin deficiency, C282Y homozygous hemochromatosis, Wilson's disease, drug- or toxin-induced liver disease, alcohol-related liver disease, primary biliary cirrhosis, sclerosing cholangitis, and porphyria cutanea tarda causing liver pathology or requiring phlebotomy * Patients with a history of liver cell cancer, screening before or screening suspected hepatocellular carcinoma (HCC) patients, or imaging studies found suspicious nodules, or AFP \> 50 ng/mL * Positive hepatitis A antibody，positive hepatitis B surface antigen，syphilis antibody or HIV antibody at screening * Others as specified in the detailed protocol