Vitamin D deficiency is known to be significantly associated with high myopia. This study investigated the vitamin D status in patients with high myopia and primary open-angle glaucoma, in order to understand the relationship between high myopia and the development of primary open-angle glaucoma.110 primary open-angle glaucoma patients, 110 high myopia patients and 110 age-matched people in the Han population were enrolled. Serum levels of 1a, 25-Dihydroxyvitamin D3 were measured by an enzyme-linked immuno-absorbent assay.Vitamin D receptor polymorphic analysis was studied by polymerase chain reaction-restriction fragment length polymorphism technique.
Study Type
OBSERVATIONAL
Enrollment
500
Tianjin Medical University Eye Hospital
Tianjin, Tianjin Municipality, China
Serum levels of 1a, 25-Dihydroxyvitamin D3
Time frame: 1 day visit
gene polymorphisms of vitamin D receptor
Time frame: 1 day visit
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