The purpose of this pilot prospective randomized control trial is to compare the initiation of labor epidural analgesia by combined spinal epidural vs. epidural for the influence on risk for postpartum depression symptoms. Investigators will randomize women to the receipt of CSE or E during labor, after measuring baseline psychological, psychosocial, and psychophysical factors related to pain and depression. The immediate research goals are to understand whether the association between labor pain and PPD is modifiable through the use of tailored anesthetic techniques.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
PREVENTION
Masking
DOUBLE
Enrollment
61
Magee Womens Hospital of UPMC
Pittsburgh, Pennsylvania, United States
Edinburgh Postnatal Depression Score (EPDS)
Self-completed questionnaire, electronically completed. Scores range from 0-30, with higher score indicating higher likelihood of depressive illness. A score of 10 or greater is characterized as possible depression.
Time frame: 6 weeks
Pain Score on Average (BPI - Short Form)
Self-completed questionnaire, electronically completed. Pain scores range from 0 (no pain) to 10 (pain as bad as you can imagine). Participants only answered this question if answered "yes" to question: "Have you had pain other than everyday kinds of pain today?"
Time frame: 2 days postpartum
Pain Score on Average (BPI - Short Form)
Self-completed questionnaire, electronically completed. Pain scores range from 0 (no pain) to 10 (pain as bad as you can imagine). Participants only answered this question if answered "yes" to question: "Have you had pain other than everyday kinds of pain today?"
Time frame: 6 weeks postpartum
Pain Score on Average (BPI - Short Form)
Self-completed questionnaire, electronically completed. Pain scores range from 0 (no pain) to 10 (pain as bad as you can imagine). Participants only answered this question if answered "yes" to question: "Have you had pain other than everyday kinds of pain today?"
Time frame: 3 months postpartum
Perceived Stress (PSS)
Self-completed questionnaire, electronically completed. Scores range from 0-40, with higher scores indicating higher perceived stress.
Time frame: 2 days postpartum
Number of Participants Currently Breastfeeding at 2 Days Postpartum (Yes/No)
Self-completed questionnaire, electronically completed. Results represent the percentage of each arm currently breastfeeding at this time point.
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Time frame: 2 Days Postpartum
Number of Participants Currently Breastfeeding at 6 Weeks Postpartum (Yes/No)
Self-completed questionnaire, electronically completed. Results represent the percentage of each arm currently breastfeeding at this time point.
Time frame: 6 weeks postpartum
Number of Participants Currently Breastfeeding at 3 Months Postpartum (Yes/No)
Self-completed questionnaire, electronically completed. Results represent the percentage of each arm currently breastfeeding at this time point.
Time frame: 3 months postpartum
Parent-Infant Attachment (MPAS)
Self-completed questionnaire, electronically completed. Scores range from 19-95, with higher scores indicating higher attachment.
Time frame: 6 weeks postpartum
Parent-Infant Attachment (MPAS)
Self-completed questionnaire, electronically completed. Scores range from 19-95, with higher scores indicating higher attachment.
Time frame: 3 months postpartum
Child Development (ASQ-3) Personal Social Score
Self-completed questionnaire, electronically completed. Scores range from 0-60, with higher scores indicating higher personal-social development.
Time frame: 6 weeks postpartum
Child Development (ASQ-3) Personal Social Score
Self-completed questionnaire, electronically completed. Scores range from 0-60, with higher scores indicating higher personal-social development.
Time frame: 3 months postpartum
Parenting Self-efficacy (PMP-SE)
Self-completed questionnaire, electronically completed. Scores range from 20-80, with higher scores indicating higher parenting self-efficacy.
Time frame: 6 weeks postpartum
Parenting Self-Efficacy (PMP-SE)
Self-completed questionnaire, electronically completed. Scores range from 20-80, with higher scores indicating higher parenting self-efficacy.
Time frame: 3 months postpartum
Edinburgh Postnatal Depression Score (EPDS)
Self-completed questionnaire, electronically completed. Scores range from 0-30, with higher score indicating higher likelihood of depressive illness. A score of 10 or greater is characterized as possible depression.
Time frame: 3 months