The lung is at risk for ischemic insults during total cardiopulmonary bypass because lung perfusion is maintained solely by the bronchial arterial system
The study will be performed in the pediatric cardiothoracic unit, pediatric Assiut University Hospital. After obtaining approval from the local ethics committee and written informed parents consent 60 patients will be included in this study according to the following criteria:
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
PREVENTION
Masking
DOUBLE
Enrollment
68
Low flow of mixed oxygen / air (1:1L) will be used during the period of cardiopulmonary bypass
Low rate (4\\min) with low tidal volume ( 2ml/kg ) will be used during the period of cardiopulmonary bypass.
Faculty of Medicine
Asyut, Egypt
Change from Baseline Computerized tomography chest (CT chest) within 7 days postoperative
Time frame: preoperative and within the first 7 days postoperative
Mechanical ventilation
Duration of mechanical ventilation (hours)
Time frame: Within the first 7 days postoperative
Intensive care unit stay
Intensive care unit stay
Time frame: Within the first 7 days postoperative
Intubation time
Intubation time (hours)
Time frame: Within the first 7 days postoperative
Arterial blood gases
Intraoperative and postoperative by appropriate scale
Time frame: Within the first 7 days postoperative
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