Low back pain is very common problem, variable modalities have been introduced to control such problem. One of the emerging modalities is the ozone - oxygen (O2-O3 ) mixture that could reduce the herniation disk size and inflammation.
Intervertebral disc herniation is the most common problem which induces low back pain LBP. The number of patients seek surgical and or alternative therapy increases. The rate of re-operation is between 7-9% at 2 years and increases up to 10-25% at ten years postoperative. Epidural injections with local anesthetics and steroids are one of the most commonly used interventions in managing chronic low back pain and lower extremity pain of various causes. However, despite their extensive use, debate continues on this medications effectiveness due to the lack of well-designed, randomized, controlled studies to determine the effectiveness of epidural injections in general, and caudal epidural injections in particular. Ozone in mixture with oxygen has been justified in multiple studies have been done, this study aims to evaluate variable doses of this mix upon patient satisfaction, pain alleviation over 12 month follow up period .
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
SINGLE
Enrollment
60
receive 10 ml of ozone oxygen mixture under variable dosing
Emad Zarief Kamel Said
Asyut, Asyut Governorate, Egypt
Pain alleviation by visual analogue scale (VAS)
assessing pain alleviation by visual analogue scale (VAS)
Time frame: 12 months
Reduction of disk herniation by MRI
evaluation of disk herniation by MRI 6 month after injection, in comparison to the pre-injection MRI
Time frame: 6 months
Pain alleviation using Oswestry Low Back Pain Questionnaire
using Oswestry Low Back Pain Questionnaire
Time frame: 12 months
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