Palliation of Dyspnea With Mouth Piece Ventilation in AECOPD

Inclusion Criteria: * a previous diagnosis of COPD * hospitalized due to acute exacerbation of COPD * at least moderate dyspnea (NRS = Numeric Rating Scale ≥ 4) * no acute hypoventilation (pH ≥ 7.35 and PCO2 ≤ 6.0 kPa) * able to understand the study and to give informed consent Exclusion Criteria: * unable to participate and use MPV due to e.g. delirium or lack of co-operation * acute hypoventilation (pH \< 7.35 or PCO2 \> 6.0 kPa) * acute need for ventilatory support * the cause of the dyspnea can be successfully treated * unable to give informed consent * a previous chronic hypoxemic or hypercapnic respiratory insufficiency that has been treated on a long-term basis also at home